Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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CA Renal Higgins Cluster Number 20 (109 genes) This page contains all miRNA mediated regulation and functional enrichment for CA Renal Higgins cluster number 20. Information about renal cancer can be found on Wikipedia, and further information about the "CA Renal Higgins" dataset can be found in Higgins et al., 2003. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-1261 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001775 cell activation 20 GO:0002376 immune system process 35 GO:0002429 immune response-activating cell surface receptor signaling pathway 6 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4 GO:0002682 regulation of immune system process 20 GO:0002684 positive regulation of immune system process 12 GO:0002694 regulation of leukocyte activation 10 GO:0002696 positive regulation of leukocyte activation 8 GO:0002768 immune response-regulating cell surface receptor signaling pathway 6 GO:0006950 response to stress 42 GO:0006952 defense response 27 GO:0006955 immune response 28 GO:0007165 signal transduction 43 GO:0009607 response to biotic stimulus 14 GO:0009611 response to wounding 18 GO:0009615 response to virus 9 GO:0019221 cytokine-mediated signaling pathway 9 GO:0019882 antigen processing and presentation 6 GO:0031294 lymphocyte costimulation 6 GO:0031295 T cell costimulation 6 GO:0042110 T cell activation 11 GO:0044419 interspecies interaction between organisms 14 GO:0045321 leukocyte activation 14 GO:0046649 lymphocyte activation 12 GO:0048583 regulation of response to stimulus 29 GO:0050776 regulation of immune response 15 GO:0050778 positive regulation of immune response 9 GO:0050863 regulation of T cell activation 8 GO:0050865 regulation of cell activation 11 GO:0050867 positive regulation of cell activation 9 GO:0050870 positive regulation of T cell activation 8 GO:0050896 response to stimulus 68 GO:0051249 regulation of lymphocyte activation 9 GO:0051251 positive regulation of lymphocyte activation 8 GO:0051704 multi-organism process 22 GO:0051707 response to other organism 13 GO:0060333 interferon-gamma-mediated signaling pathway 6 GO:0060337 type I interferon-mediated signaling pathway 5 GO:0065007 biological regulation 72 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-1261 TargetScan GO:0001775 cell activation 4 20 109 24 0.4627132 hsa-mir-1261 TargetScan GO:0002376 immune system process 8 35 109 24 0.3422773 hsa-mir-1261 TargetScan GO:0002429 immune response-activating cell surface receptor signaling pathway 2 6 109 24 0.1193037 hsa-mir-1261 TargetScan GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1 4 109 24 0.2099467 hsa-mir-1261 TargetScan GO:0002682 regulation of immune system process 6 20 109 24 0.1078337 hsa-mir-1261 TargetScan GO:0002684 positive regulation of immune system process 4 12 109 24 0.08987625 hsa-mir-1261 TargetScan GO:0002694 regulation of leukocyte activation 2 10 109 24 0.3832865 hsa-mir-1261 TargetScan GO:0002696 positive regulation of leukocyte activation 2 8 109 24 0.2437806 hsa-mir-1261 TargetScan GO:0002768 immune response-regulating cell surface receptor signaling pathway 2 6 109 24 0.1193037 hsa-mir-1261 TargetScan GO:0006950 response to stress 7 42 109 24 0.7955874 hsa-mir-1261 TargetScan GO:0006952 defense response 5 27 109 24 0.5842373 hsa-mir-1261 TargetScan GO:0006955 immune response 7 28 109 24 0.236474 hsa-mir-1261 TargetScan GO:0007165 signal transduction 8 43 109 24 0.6733634 hsa-mir-1261 TargetScan GO:0009607 response to biotic stimulus 3 14 109 24 0.3698925 hsa-mir-1261 TargetScan GO:0009611 response to wounding 3 18 109 24 0.5984036 hsa-mir-1261 TargetScan GO:0009615 response to virus 1 9 109 24 0.6325205 hsa-mir-1261 TargetScan GO:0019221 cytokine-mediated signaling pathway 1 9 109 24 0.6325205 hsa-mir-1261 TargetScan GO:0019882 antigen processing and presentation 1 6 109 24 0.3952712 hsa-mir-1261 TargetScan GO:0031294 lymphocyte costimulation 1 6 109 24 0.3952712 hsa-mir-1261 TargetScan GO:0031295 T cell costimulation 1 6 109 24 0.3952712 hsa-mir-1261 TargetScan GO:0042110 T cell activation 3 11 109 24 0.1986688 hsa-mir-1261 TargetScan GO:0044419 interspecies interaction between organisms 3 14 109 24 0.3698925 hsa-mir-1261 TargetScan GO:0045321 leukocyte activation 4 14 109 24 0.1625059 hsa-mir-1261 TargetScan GO:0046649 lymphocyte activation 3 12 109 24 0.2530651 hsa-mir-1261 TargetScan GO:0048583 regulation of response to stimulus 8 29 109 24 0.135043 hsa-mir-1261 TargetScan GO:0050776 regulation of immune response 5 15 109 24 0.07518521 hsa-mir-1261 TargetScan GO:0050778 positive regulation of immune response 3 9 109 24 0.1053623 hsa-mir-1261 TargetScan GO:0050863 regulation of T cell activation 2 8 109 24 0.2437806 hsa-mir-1261 TargetScan GO:0050865 regulation of cell activation 2 11 109 24 0.4525182 hsa-mir-1261 TargetScan GO:0050867 positive regulation of cell activation 2 9 109 24 0.3129898 hsa-mir-1261 TargetScan GO:0050870 positive regulation of T cell activation 2 8 109 24 0.2437806 hsa-mir-1261 TargetScan GO:0050896 response to stimulus 13 68 109 24 0.7603772 hsa-mir-1261 TargetScan GO:0051249 regulation of lymphocyte activation 2 9 109 24 0.3129898 hsa-mir-1261 TargetScan GO:0051251 positive regulation of lymphocyte activation 2 8 109 24 0.2437806 hsa-mir-1261 TargetScan GO:0051704 multi-organism process 5 22 109 24 0.3428689 hsa-mir-1261 TargetScan GO:0051707 response to other organism 3 13 109 24 0.3106392 hsa-mir-1261 TargetScan GO:0060333 interferon-gamma-mediated signaling pathway 1 6 109 24 0.3952712 hsa-mir-1261 TargetScan GO:0060337 type I interferon-mediated signaling pathway 0 5 109 24 0.7192331 hsa-mir-1261 TargetScan GO:0065007 biological regulation 15 72 109 24 0.573962

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